March20, 2023

Abstract Volume: 7 Issue: 2 ISSN:

Chondrofibroma -A Case Report

Dr Vaibhav Shah *1, Dr. Manjula .M 2, Dr. Manjunath. B 3, Dr. Shyla. H. N 4,
Dr. Ganapathy. K. P 5, Dr. Harish Kumar 6, Dr. Pawan 7  

Corresponding Author: Dr Vaibhav Shah, .

Copy Right: © 2023 Dr Vaibhav Shah, This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Received Date: February 17, 2023

Published Date: March 01, 2023

Chondrofibroma -A Case Report


Chondrofibromas   are benign tumours   of   Mesenchymal tissue composed of hyaline cartilage.  Chondrofibroma   means presence of cartilaginous tissue in the fibroma. Chondrofibroma is an uncommon tumour in gnathic sites.  They are thought to arise from vestigial cartilaginous rests. It can occur at any age   (commonly   between 3rd or 4th decades) of life. Chondrofibromas related to oral cavity have been reported to occur in extra osseous   and   intra osseous locations.    Extra osseous    lesions   are   found   on the lateral tongue, in soft tissue of the cheek. They can be present by birth or even in 3rd or 4th decades of life as firm, painless, mucosa covered nodules.   Chondrofibroma   can become malignant, locally infiltrative and difficult to eradicate if left untreated. At   times   they may behave   as low grade chondrosarcomas. The   paper   presents a case of   chondrofibroma treated.

Case Report

A patient aged around 19 years reported with a chief complaint of skin growth in front of the both the ears since birth.

He wants to get them removed though they didn’t cause any functional discrepencies because it affected his looks and he was teased by his friends. 

Family history:  One of his cousin has a same type of growth in front of the ear. 

Extraorally: - The submandibular, Preauricular and postauricular lymph nodes was non tender, not palpable. TMJ non tender, no deviation seen and no clicking sound heard.

Intraorally: -   patient has high narrow arched v shaped palate, two deciduos teeth retained, all third molars not erupted. No abnormalities detected in the soft tissues intra orally.


On examination:

The skin growths were present one on each side on the tragus, measuring about 0.5 -1 cm in size, the skin on the growth appeared normal, no pulsations seen on the surface, there was no discharge from the growth.                                                    

On Palpation:

There was no rise in temperature on the growth, the growth on the left side was soft in consistency whereas on the right side it was firm and cartilaginous extension from the tragus was felt. The growth was non tender and not compressible.

Provisional Diagnosis

Made based on clinical examination & history as   Lipoma/ fibroma/chondroma.

Treatment Plan

Surgical excision & sutures placed, specimen for histopathology for report, Patient to be recalled after one week for suture removal & follow up.


Basic investigations like Hb%, clotting time, bleeding time, RBS were done. The report revealed all readings were under normal limits.             

Surgical Procedure

The surgical area was prepared by cutting the hair around the lesion, then scrubbing the area with povidone iodine. Left side; Local anaesthesia was obtained by infiltrating the 2% lignocaine with adrenaline around the growth. The growth was small and soft in consistency.  The growth was held with Addison’s tissue holding forceps and using a no.11 blade excision was done.  Sutures were placed with 5-0 vicryl.

Local anaesthesia was obtained by blocking the preauricular nerve using 2% lignocaine with adrenaline.  The growth on the right was little larger and there was cartilaginous extension. Therefore, the incision was made on the crest of the growth to expose the cartilage, skin was undermined to reach the depth of the extension.                                                             

The growth was extended from the tragus. The excess growth was trimmed and reshaped, excess skin was also trimmed. Then the sutures were placed using the 5-0 vicryl.  Wokadine spray sprayed on the sutured area and patient was advised to take tab. Diclofenac and cap. Amoxicillin thrice daily for 5 days.  Patient was recalled after one week for   follow suture removal and follow up.    Both specimen were collected in two different formaline bottles, labelled and sent to histopath for obtaining a final diagnosis.

Histopathology Report                                                                      

The histopathological report revealed that the lesion was diagnosed as the chondrofibroma. The histological pictures were as follows.

The histological pictures show sub epithelial layer, connective layer, adipose tissue and the plenty of chondrocytes and fibrocytes in the connective tissue suggestive of cartilage.  The H & E stains shows the bundles of collagen fibres, fibrocytes and plenty of chondrocytes. Chondrocyte are well encapsulated binucleated cells.


Very few cases of chondrofibromas are reported in the literature.

According to Jonathan & Lamb survey the incidence of chondrofibroma among the hand bone tumours was around 1.5%.  Incidence of chondrofibroma in the head and neck region is even rarer. One case of chondrofibroma of the trachea was reported in the year 1936;

The etiology of Chondrofibroma is thought to arise from the vestigial remnants of the cartilagenous can occur at any age, with no sex predilection. Chondrofibroma may have a tendency for  transformation into chondromyxoid fibroma, which have a high tendency for malignant transformation as chondrosarcoma.

Chondrofibromas can be treated surgically by excision or through intra dermal injections.

In case we opted for surgical excision because lesion was small, accessibility was good and the treatment would get over in one visit.  The intra lesion injections take long time for healing, they require patient’s   frequent visits to hospital and patient will have to undergo the pain of injection everytime. Some patient may develop allergy for the solutions.  Cryosurgery requires sophisticated equipments, costly and if slight negligence also causes the death of the neighbouring tissues.


Chondrofibroma can be left untreated, those causing pain by pressure on surrounding structures should be excised and curetted to remove the traces of tumor cells.

Some more studies have to be conducted and report of all treated cases should be added to the literature for the benefit of the surgeons.

A simple skin growth in our case was diagnosed as chondrofibroma!

Therefore all Excisional   biopsies should be sent for HP to make a final diagnosis and reporting should be done.



1. Enchondromata of bones of the hand. A review of 40 cases. (Jonathan & Lamb) The Hand  -Vol6 No. 3; 275; 1974   

2. Chondrofibroma of the trachea. Report of a case. (Gatewood E. T): Arch. Otolaryng. 24: 92, 1936

3. Chondromyxoid fibroma of the mandible diagnostic image cytometry findings and review of the   Literature. (Susan Muller, DMD, Ms, Bryan Whitaker, DDS)Oral Surg Oral MedOral Pathol; 73; 465-8; 1992

4. Text Book of Oral Pathology by Nevil.

5. Beily and Love’s Text Book of Short Practise of Surgery. 

6. Shier’s Text Book of Cysts and Tumours.

7. Intra oral distraction for mandibular lengthening; technical innovation (P a Diner, E-M Kollar, journal of cranio-maxillofacial surgery; 24; 92- 95; 1996.

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