March29, 2023

Abstract Volume: 3 Issue: 5 ISSN:

A Comprehensive Review on Chronic Disease

Yasir Nawaz1, Ishrat Nazar2, Muhammad Kaleem Ullah*, Kashif Nawaz3, Muhammad Saleem Khan4, Bilal Saeed5, Arslan Sarfraz6, Arooj Fatima7, Khadija Iqbal8, Rao Zahid Sattar9

1,2,4,5,6,7,8,9. Department of Zoology, University of Okara, Okara Pakistan.

Corresponding Author: Muhammad Kaleem Ullah, Department of Zoology, University of Okara, Okara Pakistan.

Copy Right: © 2021 Muhammad Kaleem Ullah. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.  

Received Date: November 05, 2021

Published Date: December 01, 2021


Chronic infection conclusion in an excessive hardship certainly anguish and extinction extending throughout the entire world, concern greater in size over affecting adjacent decade involving the heart and blood vessels infection, chase aside cancer, chronic respiratory infections with diabetes mellitus, exhibit, affecting chief causation certainly annihilation cause certainly chronic infection are multi factors infection, affecting Chief etiologically aspect commence play aside different behavior aside environment hazard circumstance.

Dignity assets having the characteristics of a family with civil force has been additionally greater in number act in determining chronic infection both Immediately and indirectly aside greater in number the vulnerability behavior hazard component Chronic any deviation from a healthy conclusion in chronic signs which effective deteriorate affecting patient.

Attribute certainly activity along with worked accommodation additionally conclusion in s convincing civil and budgetary hardship. Civil hardship established with affecting accelerating exercise -proportions variation conclusion is small in range the quality of moving freely, housebound, affecting end sequence clash and consistent stigma, chronic infection inhibition focus above behavior hazard modified for the most part designate distinct civil action by chance elongate straight line many behavior hazard aspects are represented aside social intercede activity.

Keywords:  Chronic infection, Anguish, hazard aspect, civil hardship, civil action, global health strategy.

A Comprehensive Review on Chronic Disease


A chronic disease is a non-contagious disorder that continues an extensive time, grows slowly, and is produced by genetics, the environment, or a wicked routine. Chronic illness was responsible for more than 28 million (57 percent) of all global fatalities in 1990. This figure climbed to 36 million that is 63 percent of worldwide mortalities in 2008 and 39 million that is 72 percent in 2016(Anderson & Durstine, 2019).

A chronic illness is defined as “a physical or mental health problem that lasts longer than a year, creates functional limitations, or necessitates continuous monitoring or treatment.” In the United States, chronic illnesses are among the most common and expensive health problems. At least one chronic illness affects over half of all Americans (almost 45 percent, or 133 million), and the number is increasing. Chronic diseases are serious health complications that can lead to hospitalization, long-term impairment, poor quality of life, and death, according to the World Health Organization (WHO). In the United States, chronic illnesses are the leading cause of death and disability. (Raghupathi & Raghupathi, 2018).

Chronic illness is defined by the World Health Organization (WHO) as a disorder that persists a long time, grows slowly, and is not delivered down from individual to individual. According to the 2013 Global Burden of Illness training, there was a considerable (42.3 percent) increase in years lived with disability from 1990 to 2013. Chronic illness multi-morbidity is common in industrialized nations, and its prevalence rises with age according to Australian data, about 40% of persons over 44 years old have chronic disease multi-morbidity, rising to roughly 50% for people aged 65–74, and 70% for people aged 85 and above. (Reynolds et al., 2018).

Chronic illnesses are a major source of morbidity and mortality throughout the globe, putting a significant financial and public load on society (Yach et al., 2004). The most public reasons for mortality, according to the World Health Organization's Global Status Report on Noncommunicable Illnesses (2010), are heart diseases (48%) followed by malignancies (21%), chronic respiratory diseases (12%), and diabetes (3%). Over the next few decades, the global prevalence of chronic illnesses is expected to continue to rise (Roca et al., 2015).

Chronic illnesses influence and modify the lifestyle of patients, as well as the mode they understand their bodies. Patients may struggle with concerns like personality and self-esteem, as well as a more imperfect lifeworld and a harsh reality. Chronic illnesses become a part of the patients' lives, whether they influence their bodily health and roles, autonomy, independence, and personality, or endanger their lives (Benkel et al., 2020). To manage stressful events, patients with chronic diseases must discover fresh techniques to manage their changing condition and create managing techniques that connect to the mode they think and act. Depending on the individual's nature, this may involve difficulties or emotionally oriented managing (Folkman & Moskowitz, 2004).

willat (2016) study about the prevention of chronic disease and reported that chronic diseases such as diabetes, ischemic stroke, kind of cancer and chronic artery disease are the main source of mortality in high-income countries. They also concluded that chronic diseases increase in the migrant who move from low-risk countries to high-risk countries. This finding indicated that chronic diseases are not due to the genetic cause but environmental factors are also primary determinants for these diseases. Environmental factor includes lifestyle and diet which cause chronic diseases. As chronic diseases are important in western countries so most studies were conducted there which concluded that the modification in diet and lifestyle was helpful in the prevention of many chronic diseases such as cancer diabetes and stroke. Furthermore, many developing countries had control these diseases with low medical facilities by controlling environmental factors. 


Bauer 2014 concluded that diseases are a major factor for mortality worldwide. Even two-third of deaths are caused due to these diseases. In the USA disability, poor health and deaths are mainly caused due to chronic diseases. That's why healthcare expenditures are mostly due to chronic diseases. The burden of chronic disease is mainly caused due to a list of risk factors including physical inactivity, poor diet, hyperlipidemia, tobacco use, blood pressure and alcohol consumption. The Centre for disease control and prevention uses four strategies to meet the burden of chronic diseases. these strategies include

1. Epidemiology is done to monitor the spreading of disease.

2. Mental approaches to sport the healthy behaviour and promote the health

3. Health system intervention for effective use of prevention and clinical services

4. Community resources linked to clinical services for improved management of chronic diseases. 

kverdar ( 2016) found that have of adults in America are affected with chronic diseases and these diseases are major causes of death. America is unable to control these chronic diseases even by using most of the healthcare expenditure. 

The major cause of this failure of the health care center is that this treatment requires many changes in behavior as well as in lifestyle to manage effectively this disease.


It is concluded that chronic diseases are non-infectious diseases that result in response to the environment and genetics. It lasts for more than a year. It is more common in the United States. Its treatment is very expensive and results in high rates of mortality. Mainly non-communicable illnesses result in heart diseases, diabetes and respiratory disorders. Chronic diseases change the lifestyle of patients. For the better management of the disease, patients have to cope with the new techniques to fight the disease. 



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